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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e817df3cca06ab5812f5ce35dce844310a9be35f8cf1abf4d47b89a21199d69' 
  AND token = 'lCfxl8ZZ2fckcrROegf3/EbhcRj8hhLs3UfaKoQ+wcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}