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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4b253d09cd1a12156146ad5282d6ce918614463d7101de43ffdb86ebe954ff' 
  AND token = 'r6oBK9ci4GCN7vYP4hJRXaO8Wzco1XnvzvYYz8zR5ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}