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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dff6e06b5542d8bb7b071b8a03c1dc2b8724c39917a5656f87043596c59dd80' 
  AND token = 'KVeOoE83yH06uMYKtWv00X0D7V6LerEaxD91POJsMT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}