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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c42f9e05a836129ff50d0bbe809cc267c77b68b83d86e2398421bd8363e7f1b' 
  AND token = 'vjG5NEDlmGAHYRHBwM27Jb4WZH79qUSLm1B4OabdccM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}