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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b777bd0a76d04a5009ac87df01f7e30a03d9d8cf29a18d671b491d2fdaf1436' 
  AND token = 'N0sqpvwD4aQjCFWJxjWpTVoXyU5aMZm8WdpxViIenz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}