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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e224772048cd9134c67fc4576408c667883ea3e7ee23e66c040d30f55315191' 
  AND token = 'lXZb50G2muJVzHmMqX/bn7br+PKLssW3OfDndbN60GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}