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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46009f3145e91393cd5a10ab006e8efa9a6055e16394db9ad8bf7801130e0aa9' 
  AND token = 'NLzTQAb5Rux1Vm4I2XTi+fIJTSNfBtUYY5QhfaX035c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}