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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '070f1cac8ff31d60d2fb60cbc0227b4aaf9bfc52f60ece35b664654ccac407e1' 
  AND token = 'yKWlNUNRX2md/Nb2NVStPZ2l8iNsTF2qfV9UbcJ8nvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}