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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6340f36fdb91ed282a491b33a86b0b2b1d04e850718e588d9524dbc289f0dd' 
  AND token = 'dIrfAdalyAgy/wbaNXfjqeQa5JRvogsuM3Y3G2Jh7W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}