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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ee0ca336429d2435dcb660f08552e820b1dfc2691918c6216c2e684911605f' 
  AND token = 'Tfgc6D3R4naNFxe5IsKFdqHADgMIZUHzz1RAKcv5Y00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}