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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e63782b0a44050b2b47ea00638bde5bb7f2fad39008f0f1ba4f2fbe716ef7471' 
  AND token = 'vO2mL0Vq3KaobPCq/tD6fitN/6rH+NS4MITd8b30wKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}