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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0875ffae49fd394106e790f84e0f41ce9000ee3e00ded441d729002ab133bf8' 
  AND token = '45mWtWBZY7Zrl9k+3hiiIHrctaBhP/wSWLFrMn5eaVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}