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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52bf167d7497991f707cbe68e08ce6ab739202d940d3df9c233180d076a09e9' 
  AND token = 'pQI0pfOyob36o7Pt4ke3PTTwmquVRFsEsp8GC2FDna8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}