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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678a6d488c750480942f80672220e50fc129e666d907bfc2053aa53de7d363be' 
  AND token = 'tFF4n1+tizrR3Z6DeT0BucW8bhZAoeRJQ5rNun78uFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}