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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9642bfb2f09452bbe937e666f52161fdbc8e585f60d031cfd1ac6bc730504bf' 
  AND token = 'JR/1AKefO85PHdk+esuFeNgufpvjuDH5AgcZmcb0/xI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}