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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1220fefa32560ca6ac1c8812772f1fdfcccbb7023b8d69265053cab0eb7b1fa4' 
  AND token = 'PLtL0l/HVXnVBsyOyt1kNfq26d6zhuXwykvam4dGkn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}