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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610f5022e2b80633315c9d4c13751e61cc5852abc9843b5e8881dd1cc33e8525' 
  AND token = 'XVyeFScIu8uL+mZZwm3nPK0+6B60CAuBxeYTGphsppc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}