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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a2c02a1a58cf0cd70b41c857079bb7c20aaedd7c61e773a9b177d4d3b08493' 
  AND token = 'hO+mavX1vD4y6jSGwxgUrmFyirzwcpXjMqzTUkjJu8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}