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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfaa3b807ac6d5e0afcafc3d5a5941cbd86c3ca7b7c6bc27e3d189abd41c6149' 
  AND token = 'pIUwh1XLhb50JhrOkwc5mlj9oOUc+NgC1pRMZMmxmoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}