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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c86309b66f3aebb62862d8208d0311629e9e48db2f27a8c796d34defa24d2b3' 
  AND token = '8+WuYdMaS+ZghDPSw5z+IXzyv3WsOOy4s64oAkbbibw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}