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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abac1c150445ce0d42a39128df434c3c9b04b9db7a92b04f2b9fabbf099e95f2' 
  AND token = 'EcB8+GstK0QBOGBOtCCKB6wYw4cu750Zy2FyMR4IXAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}