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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1676f3552c4bd346eccfa37943cb28b2b180d4e47c1b73ac0cfb7f63a1130922' 
  AND token = 'QUoWWPd+bqbjeQveFmq2gnY6X38u6JiXw1yUaN7mf8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}