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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41472f7a2d2d2adbbcbfa8df72b7394e4227b748f5b7e9339e8ead8a9af0567' 
  AND token = 'arDCUpqlt+EfFE2jPTbFx7k0ob+ufHbzY6tLp3UTgbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}