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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f2720e268a73efb36f33dfbfd644d3141f79e669ecfecbe4ca74035f76ed42' 
  AND token = '1kY1NcDpaVu8GPW6nu3Xp5j/DuXWZlyux3KKAyeLZBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}