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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a543e1a740e7a452c5ab30751b86768e0f0b42e65421b77b5cc9c716e8b2c96' 
  AND token = '0QFpzxSXRM6N24K0RVQzsM5rsJkrUz4/nEm6kLYjbjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}