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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d25460ae4cd25fa2955fa981e21328403f0157600ee26080d078b18f72b20f' 
  AND token = '+4PmpWKj6RMOSptGAiP32HOrKvMzB92eTzSkljniyzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}