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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b017b08bae1d3f6296571f5e7edd89cf570f713ab24b7debd90ff1353d0ffac8' 
  AND token = 'OXYUC3s5yIP4IoGGS07J9jzVmQFNhFpJd3O1P9GHkxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}