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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6b4de9921b7e579f6f8529de0fffb29f67fdb059a12d039e741423c66481b3' 
  AND token = 'C2FB7UEYJdIgd/VnngIakJF2hxpEFg6NPEMJ7W2V6SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}