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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52afe4c2c5590e495466739e1425317ef8d2e4bb237f6f894aee1d024c948b0a' 
  AND token = 'sNv4XusALipuyTnvGvPul0NllwZD3fHp97We1HYJ8mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}