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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c48d250ee105d6e910c9fba1301665ddbc5ff81761ce6b1121cf5a1edb501e' 
  AND token = 'ZUBjgmAcEzR07ui5O3iBDZHLnRzxbDnltnFWrXSlF3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}