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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821baf2087397070ef5d07d8f99e431cd3cdec71debf9afc2102ece518310b65' 
  AND token = '/A+Cw6RyP5lD3V9nZWG9RWGFxJpcPQNhWCk03oI5Lus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}