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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e7fa433c3eb186ee05b58728f286252b831f653b5118cf4bd0d6acdf6f829e' 
  AND token = 'd/z45ozOyJw2+1Bx+Ll0O+XLwg1gl+0zr7lF2N1k2UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}