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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6cf492ddee989120e63d6591cd4cbbb97244acb8cfd21b46925e445c1604d7' 
  AND token = '4/Tl8J2EkTzM9V8OqXP6i+ABbaM/6M/dL/VD/VD9b7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}