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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21c2bf198d68adb1cfbf87fa1fa6ebfd17f72cd6fa936c99d8488898814590d' 
  AND token = 'g8Nz2VVqV+QQueH1dOXOTX2d/vXcdZkqk2sMZ+Ag3eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}