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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a5a4fa0b1bf2bb9ead30d5e12fc79905c4651551110e619e413cfdd12342a0' 
  AND token = '0AVyO2O+fSKISyZ9sOSDfJe/fAHo4TngJxLKsqN6tQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}