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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722c1d8d023825f4dd8371eee0d61ae77fbdf2747c43506fca60339a2e45e198' 
  AND token = 'uO/tzdQWy1lSeKDxrntBwKxAWh5nX/X/qCz89E2KQqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}