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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1073575a22335186b466faba9a68a2aed50e97e3f286ac848bdec3711f0ccfdb' 
  AND token = '9mGy8rP019zbZf1iGt8zsdMerd6kMO8v15WBsq8kAs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}