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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cedc33183a2955d9ad287936c7becffd49336335ba8c11c2c898c646e9d0e3d' 
  AND token = 'a5Jrao9XCooXjQj840S+y+Hm/VrKPhzu9wBWXNZ4KtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}