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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b815303e4762c262fc61911799f2816a4266cf4af74a21eb4a3403c7a159b0' 
  AND token = 'MPRN0Chcgu3oWcDoyf1+RltZzp1m2vi5tEgH63+xJYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}