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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0244a56176dc9e310d5bbb98189b4a92dc975e1f5082cc45460e810fa7d878dd' 
  AND token = 'gd+t19UPoI9f23Yealh9P0aLsTG2x+AEt5F/aL66SD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}