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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c7c169202e1f1c2c67ca86d895dd04773fb2a9a122de9c4aa953144ea2ea4c' 
  AND token = 'bIDgkxTaWzuoQegD8cNNgw8Kx9VlQi9v9VGOj3mfWcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}