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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ebb350fae3ff05ba6f00e84b0aaf9dea7fe4a8cb0e6cfd1c04b1ec251cb8194' 
  AND token = 'XW0Xcr8II0pTcCqn/nytAXDTV3LmdrNWuGcXU9ic3co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}