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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fad02a6fcb5b3880a18acbe9b5bd02b0e8ab3451d8297dda8b9a7c3d07e446' 
  AND token = 'wtdmGGdX/SJMbangrzvv2O0jUln26qeSN7hTSH7AJBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}