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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2130a246f63afbc2a1ef7c1b39947d8d666ff1a3f688b8db75a61d8fb9bdeb05' 
  AND token = 'CxcUdT6HEsc1j4qSjjdIlwDUvoAeX4YEx3b/p2Q5zqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}