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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1b595b5f670b961f84845b02c818a94afe7c3c972cc84613f6a1ed3f2c3148' 
  AND token = 'ykIzL0W5y5/9lWjSyi8QezZFY/9CSYFpJ/CoQThSUv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}