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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010f03f5aba45ce158173d7991b2f1f1641fe04a412bafc72e18ae63320b8a80' 
  AND token = '/0VW/vrbjOKeHpIht5BPr79RiER6oMJQvMCjKs02SOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}