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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d4f57905ad31e366862179072fc59114c56cd753a73e116457d9b1f93ab5d8' 
  AND token = 'TiDlm1TIKdG94I1UYqLdIe21yuwnrdpKpb91WO7p3vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}