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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea7f0b7e32bbab39bceb5e553d16b009b19503790b46451ad124de9f4bd1921f' 
  AND token = 'WOYK75/WXJLMJ5yR8cKSduye9owt4L+qPeP0xDL14Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}