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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f491f47d1c89f031e49665e2620af3eaf65ac710eb0ac71f97851ffaa64efc8' 
  AND token = 'MXidp/mJUQ6JUEY+lek0epZISUjTOV1Q4nbGDcXHyS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}