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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f297f5b523e1cae7aaab32d833bc8e6032d0b3fb11b8e4aca41578e9b8e76d' 
  AND token = 'a0uKTA8EOm/YXSrxS/g/YtgTaf7X+J7xo+bqoAZnuOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}